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Noladin

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Noladin

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Noladin
formula di struttura del noladin
Nome IUPAC
5Z,8Z,11Z,14Z-Eicosatetraen-2-gliceril etere
Nomi alternativi
2-arachidonil gliceril etere 2-AGE
Caratteristiche generali
Formula bruta o molecolare	C₂₃H₄₀O₃
Massa molecolare (u)
Numero CAS	222723-55-9
PubChem	6483057
SMILES	`CCCCCC=CCC=CCC=CCC=CCCCCOC(CO)CO`
Indicazioni di sicurezza

La noladina (2-arachidonil gliceril etere, 2-AGE) è un mediatore lipidico della classe degli endocannabinoidi.

Bibliografia

Hanuš L, Abu-Lafi S, Fride E, Breuer A, Vogel Z, Shalev DE, Kustanovich I, Mechoulam R. 2-arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor. PNAS 98, 3662 (2001) Full text
Fezza F, Bisogno T, Minassi A, Appendino G, Mechoulam R, Di Marzo V. Noladin ether, a putative novel endocannabinoid: inactivation mechanisms and a sensitive method for its quantification in rat tissues. FEBS Lett. 2002 Feb 27;513(2-3):294-8. Abstract
J. L. Shoemaker, B. K. Joseph, M. B. Ruckle, P. R. Mayeux, and P. L. Prather. The Endocannabinoid Noladin Ether Acts as a Full Agonist at Human CB2 Cannabinoid Receptors. J. Pharmacol. Exp. Ther., August 1, 2005; 314(2): 868 - 875. Abstract